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pandora essence Side effects related to steroids were not found.Conclusion Prophylactic administration of steroids in multidose regimens before planned extubation reduces the incidence of laryngeal oedema after extubation and the consequent reintubation rate in adults, with few adverse events.IntroductionCritically ill patients and those undergoing surgery routinely undergo endotracheal intubation to facilitate mechanical ventilation in the intensive care unit and operating room.1 As these patients recover, respiratory support is gradually reduced until the patient can breathe unaided and the endotracheal tube can be removed. Although extubation is generally uneventful, in some patients mechanical irritation by the endotracheal tube causes substantial laryngeal oedema,2 despite use of a high volume and low pressure cuff3 w3 or laryngeal ultrasound monitoring.4 Laryngeal oedema, one of the most common complications, can result in stridor and dyspnoea and need for reintubation.3 Such complications pandora uk, particularly reintubation, might lead to a prolonged stay in intensive care, additional costs, potential morbidity, and mortality.5 Any intervention that increases the chances of successful extubation is therefore of great interest.To avoid airway complications, patients are often given steroids before extubation. Prophylactic steroids substantially reduce the incidence of stridor after extubation in children and tend to decrease the rate of reintubation and stridor in neonates,6 7 8 9 but the findings might not be applicable to adults because of differences in anatomy of the upper airway and the approach to airway management pandora essence.